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Rev. chil. cir ; 59(6): 417-420, dic. 2007. ilus, tab
Article in Spanish | LILACS | ID: lil-482851

ABSTRACT

Objetivo: Comparar la fuerza tensil de heridas cerradas mediante una sutura monofilamento no reabsorbible (nylon 5-0) y un polímero adhesivo (2-octylcianoacrilato). Material y Método: Estudio experimental. En incisiones de piel, utilizando conejos de la misma raza, se han realizado dos grupos de diez conejos, con dos incisiones cada uno, cerradas con 2-octycianoacrilato y con nylon 5-0 como control. Se ha valorado la fuerza tensil mediante un tensiómetro, en 2 tiempos: al 7° día (grupo I) y al 10° día (grupo II) post cirugía, y se ha tomado una muestra para análisis histológico. Los cálculos estadísticos se hicieron a través de prueba T-Student, y un p < 0,05 se tomó como significación estadística. Resultados: El valor medio de la fuerza tensil en el grupo I fue de 9,65 + 2,72 Newtons para las incisiones cerradas con 2-octylcianoacrilato y 9,28 + 3,28 Newtons para las cerradas con nylon 5-0, no existiendo diferencia estadísticamente significativa (P = 0,801). En el grupo II el valor medio de la fuerza tensil fue 10,98 +4,80 Newtons para las incisiones cerradas con 2-octylcianoacrilato, y 9,08 + 3,58 Newtons para las cerradas con nylon 5-0, no existiendo diferencia estadísticamente significativa (p = 0,357). El estudio histológico mostró mayor inflamación, celularidad, fibrosis y proliferación vascular en incisiones cerradas con nylon 5-0. Conclusiones: La sutura de piel realizada con el polímero adhesivo 2-octylcianoacrilato es tan resistente a la tracción como la realizada con la sutura monofilamento no reabsorbible nylon 5-0 y presenta menor reacción inflamatoria local al estudio histológico.


Background: Cyanoacrylate can be used for incision closure with better esthetical results, less pain and lower incidence of infections. However, it could have a lower resistance to tension. Aim: To compare tensile strength of wounds closed with a non reabsorbable monofilament suture and octylcyanoacrylate. Material and Methods: Two skin incisions were done in the dorsal area of 20 rabbits. One incision was closed with nylon 5-0 with stitches every 0.5 cm and the other was closed with 2 layers of octylcyanoacrylate. Groups of nine rabbits were killed at seven and ten days after the procedure. A skin rectangle of the wound area was removed and the tensile force of the suture was measured with a specially devised instrument. A histological study of the incision was also done. Results: At seven days, tensile strength of sutures closed with cyanoacrylate and nylon were 9.65 + 2.72 and 9.28 + 2.38 Newtons, respectively, p=NS. At ten days, the figures were 10.98 + 4.8 and 9.08 + 3.58 Newtons respectively, p=NS. The histological study showed more inflammation, cellularity, fibrosis and vascular proliferation in sutures closed with nylon. Conclusions: No differences in tensile strength of sutures closed with cyanoacrylate or nylon were observed in this animal model. Sutures closed with nylon had a higher inflammatory reaction.


Subject(s)
Animals , Rabbits , Cyanoacrylates/therapeutic use , Surgical Wound Dehiscence/prevention & control , Suture Techniques , Wounds and Injuries/surgery , Nylons , Tensile Strength , Time Factors
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